Department of Chemistry and Chemical Biology

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EchoBack CAR T-cells could be a game changer in cancer immunotherapy

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  Imagine a super-charged immune cell that can launch a focused attack on stubborn solid tumors - a smart fighter that destroys cancer cells for days without tiring. USC biomedical engineers have made this concept a reality, crafting what they have named the "EchoBack CAR T-cell," which could soon be a game changer in the field of cancer immunotherapy . The work, published in the scientific journal Cell, is a groundbreaking new approach that could overcome major obstacles in treating tumors that are not usually candidates for immunotherapy, while keeping healthy tissue safe. Chimeric antigen receptor (CAR) T-cell therapy is a promising field of cancer treatment that has shown great success in treating bloodborne cancers such as leukemia. It is a highly customized therapy in which cancer-fighting T-cells are drawn directly from the blood of a patient and given genetic modifications to enhance their ability to target and kill cancerous cells. The USC Alfred E. Mann Department ...
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New AI Tool Tracks Your Steps by Reading the Bacteria You Carry

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  Lund University’s mGPS AI tool traces recent locations based on microbial signatures, aiding forensics and epidemiology by linking bacteria to specific geographic origins. A research team from Lund University in Sweden has created an AI tool capable of tracking the most recent locations you’ve visited. Unlike a traditional navigation system that helps you reach a destination, this tool pinpoints the geographical origin of microorganisms. This innovation allows bacteria to reveal whether someone recently visited the beach, disembarked at a city center train station, or took a walk through the woods. This opens up new possibilities within medicine, epidemiology , and forensics. Microorganisms are organisms, such as bacteria, that are invisible to the naked eye. The word microbiome is used to describe all the microorganisms in a particular environment. Establishing the geographical source of a microbiome sample has been a considerable challenge up to now. However, in a new study...
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Warming Mars’ atmosphere with nanoparticles

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  Mars has emerged as the leading candidate for human expansion. Its proximity to Earth, abundant amounts of sunlight and ample water trapped in ice makes Martian colonies theoretically plausible. One significant challenge though is Mars’ thin atmosphere . To heat Mars and thicken its atmosphere in preparation for human settlement, scientists have proposed that microscopic nanorods could be released into the Martian sky to accelerate the necessary greenhouse effect. The subsequent rise in temperature would melt ice and release more CO2 , trapped in solid form on Mars’ surface, significantly increasing atmospheric pressure. Using Mars’ own resources Due to a lack of magnetic field, Mars’ atmosphere was long ago stripped away by solar winds. Multiple strategies to thicken the Red Planet’s atmosphere have been proposed but require large quantities of resources, like greenhouse gases, be brought over as they aren’t abundant on Mars. With today’s current technology, the journey to Ma...
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